The Lilywhites will come up against former PNE man Gareth Ainsworth who manager of the Chairboys.
Ainsworth played over 100 games for the Lilywhites over three spells at Deepdale and featured for North End in the 1994 play-off final against his current club Wycombe at Wembley as the club's battled for promotion to the second division.
Wycombe currently sit 5th in League Two, and have overcome Solihull Moors and Leatherhead in previous rounds to reach this stage of the competition.
The last time North End faced Wycombe was back in 2013 when the two sides clashed in the second round of the same competition, with a superb strike from Kevin Davies enough to earn North End a place in the third round.
Ainsworth played over 100 games for the Lilywhites over three spells at Deepdale and featured for North End in the 1994 play-off final against his current club Wycombe at Wembley as the club's battled for promotion to the second division.
Wycombe currently sit 5th in League Two, and have overcome Solihull Moors and Leatherhead in previous rounds to reach this stage of the competition.
The last time North End faced Wycombe was back in 2013 when the two sides clashed in the second round of the same competition, with a superb strike from Kevin Davies enough to earn North End a place in the third round.
Why should a man go to work, if he has the health and strength to stay in bed?